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Screening for inhibitor of episomal DNA identified dicumarol as a hepatitis B virus inhibitor
Currently, there is no available therapy to eradicate hepatitis B virus (HBV) in chronically infected individuals. This is due to the difficulty in eliminating viral covalently closed circular (ccc) DNA, which is central to the gene expression and replication of HBV. We developed an assay system for...
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| 出版年: | PLoS One |
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| 主要な著者: | , , , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6380541/ https://ncbi.nlm.nih.gov/pubmed/30779774 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0212233 |
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