Rosmarinic acid is a novel inhibitor for Hepatitis B virus replication targeting viral epsilon RNA-polymerase interaction

Current therapeutics for hepatitis B virus (HBV) patients such as nucleoside analogs (NAs) are effective; however, new antiviral drugs against HBV are still desired. Since the interaction between the epsilon (ε) sequence of HBV pregenomic RNA and viral polymerase (Pol) is a key step in the HBV repli...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Tsukamoto, Yuta, Ikeda, Sotaro, Uwai, Koji, Taguchi, Riho, Chayama, Kazuaki, Sakaguchi, Takemasa, Narita, Ryo, Yao, Wan-Ling, Takeuchi, Fumihiko, Otakaki, Yukie, Watashi, Koichi, Wakita, Takaji, Kato, Hiroki, Fujita, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5962091/
https://ncbi.nlm.nih.gov/pubmed/29782545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0197664
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