Anti-HIV IgM protects against mucosal SHIV transmission

OBJECTIVE: Worldwide, most new HIV infections occur through mucosal exposure. Immunoglobulin M (IgM) is the first antibody class generated in response to infectious agents; IgM is present in the systemic circulation and in mucosal fluids as secretory IgM. We sought to investigate for the first time...

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Pubblicato in:AIDS
Autori principali: GONG, Siqi, TOMUSANGE, Khamis, KULKARNI, Viraj, ADENIJI, Opeyemi S., LAKHASHE, Samir K., HARIRAJU, Dinesh, STRICKLAND, Amanda, PLAKE, Elizabeth, FROST, Patrice A., RATCLIFFE, Sarah J., WANG, Liping, LAFER, Eileen M., RUPRECHT, Ruth M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6380498/
https://ncbi.nlm.nih.gov/pubmed/29762161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000001857
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