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Mucosal IgA Responses: Damaged in Established HIV Infection—Yet, Effective Weapon against HIV Transmission

HIV infection not only destroys CD4(+) T cells but also inflicts serious damage to the B-cell compartment, such as lymphadenopathy, destruction of normal B-cell follicle architecture, polyclonal hypergammaglobulinemia, increased apoptosis of B cells, and irreversible loss of memory B-cell responses...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Kulkarni, Viraj, Ruprecht, Ruth M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686557/
https://ncbi.nlm.nih.gov/pubmed/29176985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01581
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