Inhibitory effect of HIV-specific neutralizing IgA on mucosal transmission of HIV in humanized mice

HIV-1 infections are generally initiated at mucosal sites. Thus, IgA antibody, which plays pivotal roles in mucosal immunity, might efficiently prevent HIV infection. However, mounting a highly effective HIV-specific mucosal IgA response by conventional immunization has been challenging and the pote...

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Detalhes bibliográficos
Main Authors: Hur, Eun Mi, Patel, Sonal N., Shimizu, Saki, Rao, Dinesh S., Gnanapragasam, Priyanthi N. P., An, Dong Sung, Yang, Lili, Baltimore, David
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3512234/
https://ncbi.nlm.nih.gov/pubmed/23065154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-04-422303
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