Division of labour: tRNA methylation by the NSun2 tRNA methyltransferases Trm4a and Trm4b in fission yeast

Enzymes of the cytosine-5 RNA methyltransferase Trm4/NSun2 family methylate tRNAs at C48 and C49 in multiple tRNAs, as well as C34 and C40 in selected tRNAs. In contrast to most other organisms, fission yeast Schizosaccharomyces pombe carries two Trm4/NSun2 homologs, Trm4a (SPAC17D4.04) and Trm4b (S...

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Publicat a:RNA Biol
Autors principals: Müller, Martin, Samel-Pommerencke, Anke, Legrand, Carine, Tuorto, Francesca, Lyko, Frank, Ehrenhofer-Murray, Ann E.
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2019
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6380293/
https://ncbi.nlm.nih.gov/pubmed/30646830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2019.1568819
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