Radiosynthesis and in vivo evaluation of (11)C-labeled BMS-193885 and its desmethyl analog as PET tracers for neuropeptide Y1 receptors

BACKGROUND: Neuropeptide Y (NPY) has been implicated in a wide variety of physiological processes, including feeding, learning, memory, emotion, cardiovascular homeostasis, hormone secretion, and circadian rhythms. NPY Yl receptor (NPY Y1-R) is the most widely studied NPY receptor, and is involved i...

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Veröffentlicht in:EJNMMI Radiopharm Chem
Hauptverfasser: Kawamura, Kazunori, Mori, Wakana, Fujinaga, Masayuki, Yamasaki, Tomoteru, Zhang, Yiding, Wakizaka, Hidekatsu, Hatori, Akiko, Xie, Lin, Kumata, Katsushi, Ohkubo, Takayuki, Kurihara, Yusuke, Ogawa, Masanao, Nengaki, Nobuki, Zhang, Ming-Rong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer International Publishing 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6379498/
https://ncbi.nlm.nih.gov/pubmed/31659508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41181-019-0056-5
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