क्यूआर कोड

Efficient one-pot radiosynthesis of the 11C-labeled aquaporin-4 inhibitor TGN-020

Abstract Background [11C]TGN-020 has been developed as a positron emission tomography (PET) tracer for imaging aquaporin-4 (AQP4) in the brain and used in clinical studies. Previously, [11C]TGN-020 was synthesized through the acylation of [11C]nicotinic acid, produced by the reaction of 3-bromopyrid...

पूर्ण विवरण

में बचाया:
मुख्य लेखकों: Kazunori Kawamura, Katsushi Kumata, Tomoteru Yamasaki, Masanao Ogawa, Yusuke Kurihara, Nobuki Nengaki, Yukimi Nakamura, Maiko Ono, Yuhei Takado, Hironaka Igarashi, Ming-Rong Zhang
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: SpringerOpen 2025-04-01
श्रृंखला:EJNMMI Radiopharmacy and Chemistry
विषय:
Carbon-11
Radiosynthesis
[11C]TGN-020
Positron emission tomography
Aquaporin-4
ऑनलाइन पहुंच:https://doi.org/10.1186/s41181-025-00338-7
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