טוען...
HIV-1 vaccination by needle-free oral injection induces strong mucosal immunity and protects against SHIV challenge
The oral mucosa is an attractive site for mucosal vaccination, however the thick squamous epithelium limits antigen uptake. Here we utilize a modified needle-free injector to deliver immunizations to the sublingual and buccal (SL/B) tissue of rhesus macaques. Needle-free SL/B vaccination with modifi...
שמור ב:
| הוצא לאור ב: | Nat Commun |
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| Main Authors: | , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Publishing Group UK
2019
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6379385/ https://ncbi.nlm.nih.gov/pubmed/30778066 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-08739-4 |
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