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Nicotinic Acetylcholine Receptor Agonists for the Treatment of Alzheimer’s Dementia: An Update

A significant portion of the clinical phenotype observed in Alzheimer’s disease (AD) occurs through nicotinic acetylcholine receptors (nAChRs). Degeneration of cholinergic neurons, combined with aberrant nAChR expression and activation partially through amyloid-beta peptide (Aβ)–nAChR leads to upreg...

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Detalhes bibliográficos
Publicado no:Nicotine Tob Res
Main Authors: Hoskin, Justin L, Al-Hasan, Yazan, Sabbagh, Marwan Noel
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6379052/
https://ncbi.nlm.nih.gov/pubmed/30137524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ntr/nty116
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