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Nicotinic Acetylcholine Receptor Agonists for the Treatment of Alzheimer’s Dementia: An Update

A significant portion of the clinical phenotype observed in Alzheimer’s disease (AD) occurs through nicotinic acetylcholine receptors (nAChRs). Degeneration of cholinergic neurons, combined with aberrant nAChR expression and activation partially through amyloid-beta peptide (Aβ)–nAChR leads to upreg...

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Publicat a:Nicotine Tob Res
Autors principals: Hoskin, Justin L, Al-Hasan, Yazan, Sabbagh, Marwan Noel
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6379052/
https://ncbi.nlm.nih.gov/pubmed/30137524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ntr/nty116
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