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Cholesterol increases protein levels of the E3 ligase MARCH6 and thereby stimulates protein degradation
The E3 ligase membrane-associated ring-CH-type finger 6 (MARCH6) is a polytopic enzyme bound to the membranes of the endoplasmic reticulum. It controls levels of several known protein substrates, including a key enzyme in cholesterol synthesis, squalene monooxygenase. However, beyond its own autodeg...
में बचाया:
| में प्रकाशित: | J Biol Chem |
|---|---|
| मुख्य लेखकों: | , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
American Society for Biochemistry and Molecular Biology
2019
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6378986/ https://ncbi.nlm.nih.gov/pubmed/30545937 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005069 |
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