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Retinal degeneration 3 (RD3) protein, a retinal guanylyl cyclase regulator, forms a monomeric and elongated four-helix bundle

Retinal degeneration 3 (RD3) protein promotes accumulation of retinal membrane guanylyl cyclase (RetGC) in the photoreceptor outer segment and suppresses RetGC activation by guanylyl cyclase–activating proteins (GCAPs). Mutations truncating RD3 cause severe congenital blindness by preventing the inh...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Peshenko, Igor V., Yu, Qinhong, Lim, Sunghyuk, Cudia, Diana, Dizhoor, Alexander M., Ames, James B.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6378972/
https://ncbi.nlm.nih.gov/pubmed/30559291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006106
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