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Structural basis for the specificity of renin-mediated angiotensinogen cleavage
The renin–angiotensin cascade is a hormone system that regulates blood pressure and fluid balance. Renin-mediated cleavage of the angiotensin I peptide from the N terminus of angiotensinogen (AGT) is the rate-limiting step of this cascade; however, the detailed molecular mechanism underlying this st...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6378967/ https://ncbi.nlm.nih.gov/pubmed/30563843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006608 |
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