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Structural basis for interorganelle phospholipid transport mediated by VAT-1

Eukaryotic cells are compartmentalized to form organelles, whose functions rely on proper phospholipid and protein transport. Here we determined the crystal structure of human VAT-1, a cytosolic soluble protein that was suggested to transfer phosphatidylserine, at 2.2 Å resolution. We found that VAT...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Watanabe, Yasunori, Tamura, Yasushi, Kakuta, Chika, Watanabe, Seiya, Endo, Toshiya
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7062155/
https://ncbi.nlm.nih.gov/pubmed/32005660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011019
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