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Histone demethylase KDM7A reciprocally regulates adipogenic and osteogenic differentiation via regulation of C/EBPα and canonical Wnt signalling

Recent emerging evidences revealed that epigenetic methylation of histone and DNA regulates the lineage commitment of mesenchymal progenitor cells. This study was undertaken to delineate the actions of histone lysine demethylase 7A (KDM7A) on osteogenic and adipogenic differentiation. Kdm7a expressi...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Yang, Xiaoyue, Wang, Guannan, Wang, Yi, Zhou, Jie, Yuan, Hairui, Li, Xiaoxia, Liu, Ying, Wang, Baoli
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6378189/
https://ncbi.nlm.nih.gov/pubmed/30614617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14126
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