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Alternative isoforms of KDM2A and KDM2B lysine demethylases negatively regulate canonical Wnt signaling

A precisely balanced activity of canonical Wnt signaling is essential for a number of biological processes and its perturbation leads to developmental defects or diseases. Here, we demonstrate that alternative isoforms of the KDM2A and KDM2B lysine demethylases have the ability to negatively regulat...

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Publicado en:PLoS One
Autores principales: Lađinović, Dijana, Pinkas, Daniel, Šopin, Tijana, Raška, Otakar, Liška, František, Raška, Ivan, Vacík, Tomáš
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7588095/
https://ncbi.nlm.nih.gov/pubmed/33104714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0236612
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