Alternative isoforms of KDM2A and KDM2B lysine demethylases negatively regulate canonical Wnt signaling

A precisely balanced activity of canonical Wnt signaling is essential for a number of biological processes and its perturbation leads to developmental defects or diseases. Here, we demonstrate that alternative isoforms of the KDM2A and KDM2B lysine demethylases have the ability to negatively regulat...

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Publicat a:PLoS One
Autors principals: Lađinović, Dijana, Pinkas, Daniel, Šopin, Tijana, Raška, Otakar, Liška, František, Raška, Ivan, Vacík, Tomáš
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7588095/
https://ncbi.nlm.nih.gov/pubmed/33104714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0236612
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