A demethylation deficient isoform of the lysine demethylase KDM2A interacts with pericentromeric heterochromatin in an HP1a-dependent manner

Histone modifications have a profound impact on the chromatin structure and gene expression and their correct establishment and recognition is essential for correct cell functioning. Malfunction of histone modifying proteins is associated with developmental defects and diseases and detailed characte...

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Bibliografiska uppgifter
I publikationen:Nucleus
Huvudupphovsmän: Lađinović, Dijana, Novotná, Jitka, Jakšová, Soňa, Raška, Ivan, Vacík, Tomáš
Materialtyp: Artigo
Språk:Inglês
Publicerad: Taylor & Francis 2017
Ämnen:
Original Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5703260/
https://ncbi.nlm.nih.gov/pubmed/28816576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19491034.2017.1342915
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