Histone demethylase KDM5A is transactivated by the transcription factor C/EBPβ and promotes preadipocyte differentiation by inhibiting Wnt/β-catenin signaling

β-Catenin signaling is triggered by WNT proteins and is an important pathway that negatively regulates adipogenesis. However, the mechanisms controlling the expression of WNT proteins during adipogenesis remain incompletely understood. Lysine demethylase 5A (KDM5A) is a histone demethylase that remo...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Guo, Liang, Guo, Ying-Ying, Li, Bai-Yu, Peng, Wan-Qiu, Tang, Qi-Qun
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2019
Schlagworte:
Cell Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6579482/
https://ncbi.nlm.nih.gov/pubmed/31061100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008419
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