Considerations for the use of Cre recombinase for conditional gene deletion in the mouse lens

BACKGROUND: Despite a number of different transgenes that can mediate DNA deletion in the developing lens, each has unique features that can make a given transgenic line more or less appropriate for particular studies. The purpose of this work encompasses both a review of transgenes that lead to the...

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Detalhes bibliográficos
Publicado no:Hum Genomics
Main Authors: Lam, Phuong T., Padula, Stephanie L., Hoang, Thanh V., Poth, Justin E., Liu, Lin, Liang, Chun, LeFever, Adam S., Wallace, Lindsay M., Ashery-Padan, Ruth, Riggs, Penny K., Shields, Jordan E., Shaham, Ohad, Rowan, Sheldon, Brown, Nadean L., Glaser, Tom, Robinson, Michael L.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Primary Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6377743/
https://ncbi.nlm.nih.gov/pubmed/30770771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40246-019-0192-8
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