Capturing the inherent structural dynamics of the HIV-1 envelope glycoprotein fusion peptide

The N-terminal fusion peptide (FP) of the human immunodeficiency virus (HIV)-1 envelope glycoprotein (Env) gp41 subunit plays a critical role in cell entry. However, capturing the structural flexibility in the unbound FP is challenging in the native Env trimer. Here, FP conformational isomerism is o...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Commun
Egile Nagusiak: Kumar, Sonu, Sarkar, Anita, Pugach, Pavel, Sanders, Rogier W., Moore, John P., Ward, Andrew B., Wilson, Ian A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6377653/
https://ncbi.nlm.nih.gov/pubmed/30770829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-08738-5
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