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Cost-effective and robust genotyping using double-mismatch allele-specific quantitative PCR
For a wide range of diseases, SNPs in the genome are the underlying mechanism of dysfunction. Therefore, targeted detection of these variations is of high importance for early diagnosis and (familial) screenings. While allele-specific PCR has been around for many years, its adoption for SNP genotypi...
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| Veröffentlicht in: | Sci Rep |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6377641/ https://ncbi.nlm.nih.gov/pubmed/30770838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-38581-z |
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