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Peptidic degron for IMiD-induced degradation of heterologous proteins

Current systems for modulating the abundance of proteins of interest in living cells are powerful tools for studying protein function but differ in terms of their complexity and ease of use. Moreover, no one system is ideal for all applications, and the best system for a given protein of interest mu...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Koduri, Vidyasagar, McBrayer, Samuel K., Liberzon, Ella, Wang, Adam C., Briggs, Kimberly J., Cho, Hyejin, Kaelin, William G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6377458/
https://ncbi.nlm.nih.gov/pubmed/30683719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1818109116
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