Carnosine protects cardiac myocytes against lipid peroxidation products

Endogenous histidyl dipeptides such as carnosine (β-alanine-L-histidine) form conjugates with lipid peroxidation products such as 4-hydroxy-trans-2-nonenal (HNE and acrolein), chelate metals, and protect against myocardial ischemic injury. Nevertheless, it is unclear whether these peptides protect a...

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Pubblicato in:Amino Acids
Autori principali: Zhao, Jingjing, Posa, Dheeraj Kumar, Kumar, Vijay, Hoetker, David, Kumar, Amit, Ganesan, Smirthy, Riggs, Daniel W., Bhatnagar, Aruni, Wempe, Michael F., Baba, Shahid P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6377314/
https://ncbi.nlm.nih.gov/pubmed/30449006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00726-018-2676-6
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