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Crystal Structure of Aldehyde Dehydrogenase 16 Reveals Trans-Hierarchical Structural Similarity and a New Dimer

The aldehyde dehydrogenase (ALDH) superfamily is a vast group of enzymes that catalyze the NAD(+)-dependent oxidation of aldehydes to carboxylic acids. ALDH16 is perhaps the most enigmatic member of the superfamily, owing to its extra C-terminal domain of unknown function and the absence of the esse...

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Detalhes bibliográficos
Publicado no:J Mol Biol
Main Authors: Liu, Li-Kai, Tanner, John J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6376876/
https://ncbi.nlm.nih.gov/pubmed/30529746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2018.11.030
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