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RNA-seq analysis of PHD and VHL inhibitors reveals differences and similarities to the hypoxia response.
Background: Hypoxia-inducible factor (HIF) transcription factors are well known to control the transcriptional response to hypoxia. Given the importance of cellular response to hypoxia, a number of pharmacological agents to interfere with this pathway have been developed and entered pre-clinical or...
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| Опубликовано в: : | Wellcome Open Res |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
F1000 Research Limited
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6376255/ https://ncbi.nlm.nih.gov/pubmed/30801039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/wellcomeopenres.15044.1 |
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