Low Levels of Sox2 are required for Melanoma Tumor-Repopulating Cell Dormancy

Tumorigenic cells, when facing a hostile environment, may enter a dormant state, leading to long-term tumor survival, relapse, and metastasis. To date, the molecular mechanism of tumor cell dormancy remains poorly understood. Methods: A soft, 3-dimentional (3D) fibrin gel culture system was used to...

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Bibliographic Details
Published in:Theranostics
Main Authors: Jia, Qiong, Yang, Fang, Huang, Wei, Zhang, Yao, Bao, Binghao, Li, Ke, Wei, Fuxiang, Zhang, Cunyu, Jia, Haibo
Format: Artigo
Language:Inglês
Published: Ivyspring International Publisher 2019
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6376184/
https://ncbi.nlm.nih.gov/pubmed/30809284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.29698
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