Antibody-mediated biorecognition of myelin oligodendrocyte glycoprotein: computational evidence of demyelination-related epitopes

Antigen-antibody interaction is crucial in autoimmune disease pathogenesis, as multiple sclerosis and neuromyelitis optica. Given that, autoantibodies are essential biomolecules, of which the myelin oligodendrocyte glycoprotein (MOG) can figure as a target. Here we combined Molecular Dynamics (MD),...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Ierich, Jéssica Cristiane Magalhães, Brum, Doralina Guimarães, Moraes, Ariana de Souza, Higa, Akemi Martins, Garcia, Pâmela Soto, Miyazaki, Celina Massumi, Ferreira, Marystela, Peroni, Luís Antonio, Oliveira, Guedmiller Souza de, Franca, Eduardo de Faria, Freitas, Luiz Carlos Gomide, Leite, Fabio Lima
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6376134/
https://ncbi.nlm.nih.gov/pubmed/30765742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36578-8
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