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Exploration of the binding pocket of histone deacetylases: the design of potent and isoform-selective inhibitors
Histone deacetylases (HDACs) are enzymes that act on histone proteins to remove the acetyl group and thereby regulate the chromatin state. HDACs act not only on histone protein but also nonhistone proteins that are key players in cellular processes such as the cell cycle, signal transduction, apopto...
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| Published in: | Turk J Biol |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
The Scientific and Technological Research Council of Turkey
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6375539/ https://ncbi.nlm.nih.gov/pubmed/30814855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3906/biy-1701-26 |
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