Tumoral NOX4 recruits M2 tumor-associated macrophages via ROS/PI3K signaling-dependent various cytokine production to promote NSCLC growth

M2-type tumor-associated macrophages (TAMs) infiltration contributes to cancer malignant progression. However, the mechanisms for controlling recruitment and M2 polarization of macrophages by cancer cells are largely unclear. NADPH oxidase 4 (NOX4) is abundantly expressed in non-small cell lung canc...

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Gepubliceerd in:Redox Biol
Hoofdauteurs: Zhang, Jiahao, Li, Huachao, Wu, Qipeng, Chen, Yueming, Deng, Yanchao, Yang, Zhicheng, Zhang, Luyong, Liu, Bing
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2019
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Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6374999/
https://ncbi.nlm.nih.gov/pubmed/30769285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2019.101116
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