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Baicalin ameliorates lupus autoimmunity by inhibiting differentiation of Tfh cells and inducing expansion of Tfr cells

Baicalin is a natural compound isolated from Chinese herb, which has been reported as an anti-inflammatory drug. Here, we demonstrated that Baicalin treatment could reduce urine protein, inhibit anti-ds-DNA antibody titers, and ameliorate lupus nephritis in MRL/lpr lupus-prone mice. Baicalin inhibit...

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Bibliographic Details
Published in:Cell Death Dis
Main Authors: Yang, Ji, Yang, Xue, Yang, Jie, Li, Ming
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6374440/
https://ncbi.nlm.nih.gov/pubmed/30760702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1315-9
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