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B cells control lupus autoimmunity by inhibiting Th17 and promoting Th22 cells

B cells exert immunosuppressive effects and offer therapeutic potential for systemic lupus erythematosus (SLE), but the mechanism remains unclear. Here we analyzed the B cell regulation of Th17/Th22 cell differentiation in lupus and found that α-IgM- and α-CD40-activated B cells could inhibit Th17 a...

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Библиографические подробности
Опубликовано в: :Cell Death Dis
Главные авторы: Yang, Ji, Yang, Xue, Wang, Luman, Li, Ming
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7054432/
https://ncbi.nlm.nih.gov/pubmed/32127533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2362-y
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