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Baicalin ameliorates lupus autoimmunity by inhibiting differentiation of Tfh cells and inducing expansion of Tfr cells

Baicalin is a natural compound isolated from Chinese herb, which has been reported as an anti-inflammatory drug. Here, we demonstrated that Baicalin treatment could reduce urine protein, inhibit anti-ds-DNA antibody titers, and ameliorate lupus nephritis in MRL/lpr lupus-prone mice. Baicalin inhibit...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Yang, Ji, Yang, Xue, Yang, Jie, Li, Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6374440/
https://ncbi.nlm.nih.gov/pubmed/30760702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1315-9
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