Induction of GNMT by 1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranoside through proteasome-independent MYC downregulation in hepatocellular carcinoma

Glycine-N-methyl transferase (GNMT) a tumor suppressor for hepatocellular carcinoma (HCC) plays a crucial role in liver homeostasis. Its expression is downregulated in almost all the tumor tissues of HCC while the mechanism of this downregulation is not yet fully understood. Recently, we identified...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kant, Rajni, Yen, Chia-Hung, Hung, Jung-Hsien, Lu, Chung-Kuang, Tung, Chien-Yi, Chang, Pei-Ching, Chen, Yueh-Hao, Tyan, Yu-Chang, Chen, Yi-Ming Arthur
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6374375/
https://ncbi.nlm.nih.gov/pubmed/30760754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37292-1
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