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Taming the beast: control of APC/C(Cdc20)–dependent destruction
The anaphase promoting complex/cyclosome (APC/C) is a large multi-subunit ubiquitin ligase that triggers the metaphase-to-anaphase transition in the cell cycle by targeting the substrates Cyclin B and securin for destruction. APC/C activity towards these two key substrates requires the co-activator...
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| Veröffentlicht in: | Cold Spring Harb Symp Quant Biol |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6374126/ https://ncbi.nlm.nih.gov/pubmed/29133301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/sqb.2017.82.033712 |
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