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Taming the beast: control of APC/C(Cdc20)–dependent destruction

The anaphase promoting complex/cyclosome (APC/C) is a large multi-subunit ubiquitin ligase that triggers the metaphase-to-anaphase transition in the cell cycle by targeting the substrates Cyclin B and securin for destruction. APC/C activity towards these two key substrates requires the co-activator...

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Detalhes bibliográficos
Publicado no:Cold Spring Harb Symp Quant Biol
Main Authors: Lara-Gonzalez, Pablo, Kim, Taekyung, Desai, Arshad
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6374126/
https://ncbi.nlm.nih.gov/pubmed/29133301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/sqb.2017.82.033712
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