Baboon envelope LVs efficiently transduced human adult, fetal, and progenitor T cells and corrected SCID-X1 T-cell deficiency

T cells represent a valuable tool for treating cancers and infectious and inherited diseases; however, they are mainly short-lived in vivo. T-cell therapies would strongly benefit from gene transfer into long-lived persisting naive T cells or T-cell progenitors. Here we demonstrate that baboon envel...

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Bibliographic Details
Published in:Blood Adv
Main Authors: Bernadin, Ornellie, Amirache, Fouzia, Girard-Gagnepain, Anais, Moirangthem, Ranjita Devi, Lévy, Camille, Ma, Kuiying, Costa, Caroline, Nègre, Didier, Reimann, Christian, Fenard, David, Cieslak, Agata, Asnafi, Vahid, Sadek, Hanem, Mhaidly, Rana, Cavazzana, Marina, Lagresle-Peyrou, Chantal, Cosset, François-Loïc, André, Isabelle, Verhoeyen, Els
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2019
Subjects:
Gene Therapy
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6373736/
https://ncbi.nlm.nih.gov/pubmed/30755435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018027508
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