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Repeated Administration of Norbinaltorphimine Produces Cumulative Kappa Opioid Receptor Inactivation
Kappa receptor activation by dynorphins contributes to the anxiogenic, dysphoric, and cognitive disrupting effects of repeated stress, suggesting that kappa receptor antagonists might have therapeutic utility in the treatment of stress disorders. Three classes of kappa antagonists have been distingu...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Front Pharmacol |
|---|---|
| Prif Awduron: | , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Frontiers Media S.A.
2019
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6373456/ https://ncbi.nlm.nih.gov/pubmed/30787880 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00088 |
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