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Selective JAKinibs: Prospects in Inflammatory and Autoimmune Diseases

Cytokines, many of which signal through the JAK–STAT (Janus kinase–Signal Transducers and Activators of Transcription) pathway, play a central role in the pathogenesis of inflammatory and autoimmune diseases. Currently three JAK inhibitors have been approved for clinical use in USA and/or Europe: to...

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Bibliografski detalji
Izdano u:BioDrugs
Glavni autori: Virtanen, Anniina T., Haikarainen, Teemu, Raivola, Juuli, Silvennoinen, Olli
Format: Artigo
Jezik:Inglês
Izdano: Springer International Publishing 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6373396/
https://ncbi.nlm.nih.gov/pubmed/30701418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40259-019-00333-w
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