Analyzing the Mechanisms Behind Macrolide Antibiotic-Induced Liver Injury Using Quantitative Systems Toxicology Modeling

PURPOSE: Macrolide antibiotics are commonly prescribed treatments for drug-resistant bacterial infections; however, many macrolides have been shown to cause liver enzyme elevations and one macrolide, telithromycin, has been pulled from the market by its provider due to liver toxicity. This work seek...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Pharm Res
Main Authors: Woodhead, Jeffrey L., Yang, Kyunghee, Oldach, David, MacLauchlin, Chris, Fernandes, Prabhavathi, Watkins, Paul B., Siler, Scott Q., Howell, Brett A.
Formato: Artigo
Idioma:Inglês
Publicado: Springer US 2019
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6373306/
https://ncbi.nlm.nih.gov/pubmed/30734107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-019-2582-y
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares