JHU-083 selectively blocks glutaminase activity in brain CD11b(+) cells and prevents depression-associated behaviors induced by chronic social defeat stress

There are a number of clinically effective treatments for stress-associated psychiatric diseases, including major depressive disorder (MDD). Nonetheless, many patients exhibit resistance to first-line interventions calling for novel interventions based on pathological mechanisms. Accumulating eviden...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Neuropsychopharmacology
Autors principals: Zhu, Xiaolei, Nedelcovych, Michael T., Thomas, Ajit G., Hasegawa, Yuto, Moreno-Megui, Aisa, Coomer, Wade, Vohra, Varun, Saito, Atsushi, Perez, Gabriel, Wu, Ying, Alt, Jesse, Prchalova, Eva, Tenora, Lukáš, Majer, Pavel, Rais, Rana, Rojas, Camilo, Slusher, Barbara S., Kamiya, Atsushi
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6372721/
https://ncbi.nlm.nih.gov/pubmed/30127344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-018-0177-7
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars