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Adaptive F-actin polymerization and localized ATP production drive basement membrane invasion in the absence of MMPs
Matrix metalloproteinases (MMPs) are associated with decreased patient prognosis, but have failed as anti-invasive drug targets despite promoting cancer cell invasion. Through time-lapse imaging, optical highlighting, and combined genetic removal of the five MMPs expressed during anchor cell (AC) in...
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| 發表在: | Dev Cell |
|---|---|
| Main Authors: | , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6372315/ https://ncbi.nlm.nih.gov/pubmed/30686527 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2018.12.018 |
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