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Substrate-assisted Enzymatic Formation of Lysinoalanine in Duramycin
Duramycin is a heavily post-translationally modified peptide that binds phosphatidylethanolamine. It has been investigated as an antibiotic, inhibitor of viral entry, therapeutic for cystic fibrosis, and tumor and vasculature imaging agent. Duramycin contains a β-hydroxylated Asp (Hya) and four macr...
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| Vydáno v: | Nat Chem Biol |
|---|---|
| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6372306/ https://ncbi.nlm.nih.gov/pubmed/30177849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-018-0122-4 |
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