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HIV-1 Vpu is a potent transcriptional suppressor of NF-κB-elicited antiviral immune responses
Many viral pathogens target innate sensing cascades and/or cellular transcription factors to suppress antiviral immune responses. Here, we show that the accessory viral protein U (Vpu) of HIV-1 exerts broad immunosuppressive effects by inhibiting activation of the transcription factor NF-κB. Global...
Uloženo v:
| Vydáno v: | eLife |
|---|---|
| Hlavní autoři: | , , , , , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
eLife Sciences Publications, Ltd
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6372280/ https://ncbi.nlm.nih.gov/pubmed/30717826 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.41930 |
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