HIV-1 infection activates endogenous retroviral promoters regulating antiviral gene expression

Although endogenous retroviruses (ERVs) are known to harbor cis-regulatory elements, their role in modulating cellular immune responses remains poorly understood. Using an RNA-seq approach, we show that several members of the ERV9 lineage, particularly LTR12C elements, are activated upon HIV-1 infec...

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Podrobná bibliografie
Vydáno v:Nucleic Acids Res
Hlavní autoři: Srinivasachar Badarinarayan, Smitha, Shcherbakova, Irina, Langer, Simon, Koepke, Lennart, Preising, Andrea, Hotter, Dominik, Kirchhoff, Frank, Sparrer, Konstantin M J, Schotta, Gunnar, Sauter, Daniel
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
Gene regulation, Chromatin and Epigenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7641743/
https://ncbi.nlm.nih.gov/pubmed/33021676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa832
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