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Combining Ultrasound and Intratumoral Administration of Doxorubicin-loaded Microspheres to Enhance Tumor Cell Killing

Melanoma is an incurable disease for which alternative treatments to chemotherapy alone are sought. Here, using a melanoma model, we investigated the antitumor potential of combining ultrasound (US) with poly(lactic-co-glycolic acid) (PLGA) microspheres loaded with doxorubicin (DOX). The aim was to...

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Détails bibliographiques
Publié dans:Int J Pharm
Auteurs principaux: Do, Anh-Vu, Geary, Sean M., Seol, Dongrim, Tobias, Phillip, Carlsen, Daniel, Leelakanok, Nattawut, Martin, James A., Salem, Aliasger K.
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6372090/
https://ncbi.nlm.nih.gov/pubmed/29353083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2018.01.028
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