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Antitumor Efficacy and Toxicity of 5-FU-loaded PLGA Pellets

The aim of this study was to formulate a biodegradable implant capable of imparting local anti-tumor activity through the sustained release of the chemotherapeutic agent, 5-fluorouracil (5-FU). Thus injectable pellets (< 1.2 mm diameter) made from poly(lactide co-glycolide (PLGA) and loaded with...

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Detalhes bibliográficos
Publicado no:J Pharm Sci
Main Authors: Leelakanok, Nattawut, Geary, Sean M, Salem, Aliasger K
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768445/
https://ncbi.nlm.nih.gov/pubmed/29031952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xphs.2017.10.005
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