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Fabrication and Use of PLGA-based Formulations Designed for Modified Release of 5-Fluorouracil

5-fluorouracil (5-FU) is a chemotherapeutic agent that has been used for the treatment of a variety of malignancies since its initial introduction to the clinic in 1957.(1) Due to its short biological half-life, multiple dosings are generally required to maintain effective 5-FU plasma concentrations...

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Detalhes bibliográficos
Publicado no:J Pharm Sci
Main Authors: Leelakanok, Nattawut, Geary, Sean, Salem, Aliasger
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768463/
https://ncbi.nlm.nih.gov/pubmed/29045885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xphs.2017.10.012
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