Gestational Vitamin D Supplementation Leads to Reduced Perinatal RXRA DNA Methylation: Results From the MAVIDOS Trial

We have previously demonstrated inverse associations between maternal 25(OH)‐vitamin D status and perinatal DNA methylation at the retinoid‐X‐receptor‐alpha (RXRA) locus and between RXRA methylation and offspring bone mass. In this study, we used an existing randomized trial to test the hypothesis t...

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Publicado en:J Bone Miner Res
Autores principales: Curtis, Elizabeth M, Krstic, Nevena, Cook, Eloïse, D'Angelo, Stefania, Crozier, Sarah R, Moon, Rebecca J, Murray, Robert, Garratt, Emma, Costello, Paula, Cleal, Jane, Ashley, Brogan, Bishop, Nicholas J, Kennedy, Stephen, Papageorghiou, Aris T, Schoenmakers, Inez, Fraser, Robert, Gandhi, Saurabh V, Prentice, Ann, Javaid, M Kassim, Inskip, Hazel M, Godfrey, Keith M, Bell, Christopher G, Lillycrop, Karen A, Cooper, Cyrus, Harvey, Nicholas C
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2019
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6372078/
https://ncbi.nlm.nih.gov/pubmed/30321476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.3603
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