Gestational Vitamin D Supplementation Leads to Reduced Perinatal RXRA DNA Methylation: Results From the MAVIDOS Trial

We have previously demonstrated inverse associations between maternal 25(OH)‐vitamin D status and perinatal DNA methylation at the retinoid‐X‐receptor‐alpha (RXRA) locus and between RXRA methylation and offspring bone mass. In this study, we used an existing randomized trial to test the hypothesis t...

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Detalhes bibliográficos
Publicado no:J Bone Miner Res
Main Authors: Curtis, Elizabeth M, Krstic, Nevena, Cook, Eloïse, D'Angelo, Stefania, Crozier, Sarah R, Moon, Rebecca J, Murray, Robert, Garratt, Emma, Costello, Paula, Cleal, Jane, Ashley, Brogan, Bishop, Nicholas J, Kennedy, Stephen, Papageorghiou, Aris T, Schoenmakers, Inez, Fraser, Robert, Gandhi, Saurabh V, Prentice, Ann, Javaid, M Kassim, Inskip, Hazel M, Godfrey, Keith M, Bell, Christopher G, Lillycrop, Karen A, Cooper, Cyrus, Harvey, Nicholas C
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6372078/
https://ncbi.nlm.nih.gov/pubmed/30321476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.3603
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