Childhood bone mineral content is associated with methylation status of the RXRA promoter at birth

Maternal vitamin D deficiency has been associated with reduced offspring bone mineral accrual. Retinoid-X Receptor-alpha (RXRA) is an essential cofactor in the action of 1,25(OH)(2)-vitamin D, and RXRA methylation in umbilical cord DNA has been associated with later offspring adiposity. We tested th...

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Detalhes bibliográficos
Main Authors: Harvey, Nicholas C, Sheppard, Allan, Godfrey, Keith M, McLean, Cameron, Garratt, Emma, Ntani, Georgia, Davies, Lucy, Murray, Robert, Inskip, Hazel M, Gluckman, Peter D, Hanson, Mark A, Lillycrop, Karen A, Cooper, Cyrus
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3836689/
https://ncbi.nlm.nih.gov/pubmed/23907847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2056
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